Too often, finding the right antidepressant can take a while—only a third of patients see results from the first one they try. A research collaboration spanning five countries has been working to help more people find the best treatment right away. The “International Study to Optimize Treatment for Depression” (iSPOT-D) identifies biomarkers, physical biological indicators, that can tell doctors which antidepressants will work best for which patients, and assist in the development of new ones. We spoke with Stanford University professor Leanne Williams about the project and some early results.
You can keep up with iSPOT-D and its progress by following the project on ResearchGate.
ResearchGate: For patients trying to find the right treatment for depression, what is the experience like currently?
Leanne Williams: Currently, finding the right treatment for depression involves haphazard improvisation. Patients first face the challenge of recognizing that they may have a clinical depression, which can …